<p><span style="font-size: 8pt;font-family: Arial;">The Fund aims to provide capital growth over the long term. The Fund invests at least 80% of its assets in shares (equities) and equity-related securities of companies, which are biotechnology or biotechnology-related, in any country. </span></p>


Janus Henderson Investors

Janus Henderson Investors UK Limited

Sector Equity Biotechnology

Morningstar Gbl Biotechnology NR USD

Equity

NASDAQ Biotechnology TR

Janus Henderson Hrzn Biotec A2 USD

Janus Henderson Hrzn Biotec E2 USD

2023

2022

2021

2020

2019

United States

United Kingdom

France

Denmark

China

Other countries

Unclassified

Healthcare

Amgen Inc

Vertex Pharmaceuticals Inc

argenx SE ADR

Vaxcyte Inc Ordinary Shares

Sarepta Therapeutics Inc

Sanofi SA ADR

Ascendis Pharma AS ADR

Revolution Medicines Inc Ordinary Shares

Dyne Therapeutics Inc Ordinary Shares

Biohaven Ltd