<p><span style="font-size: 8pt;font-family: Arial;">The Fund aims to provide capital growth over the long term. The Fund invests at least 80% of its assets in shares (equities) and equity-related securities of companies, which are biotechnology or biotechnology-related, in any country. </span></p>


Janus Henderson Investors

Janus Henderson Investors UK Limited

Sector Equity Biotechnology

Morningstar Gbl Biotechnology NR USD

Equity

NASDAQ Biotechnology TR

Janus Henderson Hrzn Biotec A2 SGD

Janus Henderson Hrzn Biotec E2 USD

2024

2023

2022

2021

2020

United States

Denmark

Unclassified

Healthcare

Vertex Pharmaceuticals Inc

argenx SE ADR

Amgen Inc

Sarepta Therapeutics Inc

Ascendis Pharma AS ADR

Revolution Medicines Inc Ordinary Shares

Madrigal Pharmaceuticals Inc

Soleno Therapeutics Inc

Vaxcyte Inc Ordinary Shares

Avidity Biosciences Inc Ordinary Shares